In vivo pharmacokinetics tests and sample harvest
| Model | Assay Name | Measurements |
| 1. Wild type mice | 1. P.O (e.g., gavage) | 1. Drugs or biomarker levels in plasma and key organ tissues (via subcontractors) |
| 2. Transgenic mice | 2. S.C. | 2. Histopathology and immunohistochemistry (IHC, via subcontractor) |
| 3. Cannulated rodents | 3. I.P. | |
| 4. Control | 4. I.V. | |
| 5. Treatment | 5. I.T. (intrathecal injection) | |
| 6. Mini-pump |