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Dr. Xinmin (Simon) Xie received his M.D. degree from the University of Bern, Switzerland, and a Ph.D. degree from the University of London, U.K. He is the founder and Chief Scientific Officer of AfaSci, Inc. Dr. Xie also serves as a Consulting Associate Professor at the Department of Medicine, Stanford University School of Medicine.
AfaSci was established in 2003 with the mission to create an OPEN LAB for collaborative research and drug discovery. Technological innovation and a deep understanding of the biotech research and drug discovery have enabled AfaSci to be awarded with several SBIR/STTR, and R01 grants from the National Institute of Health (NIH).
AfaSci has established research collaborations with Stanford University, SRI International, Pennsylvania State University, George Washington University and Boston VA Research Institute. It has developed a novel integrated rodent behavioral monitoring system – SmartCagetm for the automation of behavioral assays (sleep, activity and cognition) and higher-throughput screening drug screens in vivo. Recently Dr. Xie has established the new AfaSci Research Laboratory in Redwood City. While continuing to develop its technology development and conduct translational research, AfaSci now provides contract research services for in vivo pharmacology and in vitro electrophysiology to help drug discovery.
Prior to AfaSci, Dr. Xie worked at GlaxoWellcome (U.K.), Theravance (South San Francisco, CA), and Deltagen (Redwood City, CA), where he directed electrophysiologic studies and phenotyping analysis of gene-knockout mice. Between 2003 and 2008, he also established and served as the Manager of the HTS Lab, SRI International, Menlo Park, CA. He, as the Principal Investigator was awarded with NIH R03 and R21 grants and contracts. He led HTS assay development and contributed to drug discovery.
Dr. Xie was Standing Member of Center for Scientific Review, NIH (ZRG1 ETTN-D13) between 2002 and 2007. He has served as Ad Hoc reviewer for Special Emphasis Panels in R01, S10, P35, U01, U19 and U54 study sections. His grant review experience enabled him to help new principal investigators.
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